Wednesday, 4 June 2014

Duke researchers identify new brain cancer mutation that will aid drug development

A collaborative effort between Duke Medicine researchers and neurosurgeons and scientists in China has produced new genetic insights into a rare and deadly form of childhood and young adult brain cancer called brainstemglioma. The researchers identified a genetic mutation in the tumor cells that plays a role in both the growth and the death of a cell. Additionally, the mutation to the newly identified gene may also contribute to the tumor’s resistance to radiation.

Click here to read the full press release.

Study mentioned:
Nat Genet. 2014 Jun 1. doi: 10.1038/ng.2995. [Epub ahead of print]
Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.

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