Hippo ‘crosstalk’ may be vital to tumor suppression

Scientists at The University of Texas MD Anderson Cancer Center have discovered new information about a key pathway known as Hippo, a metaphoric name referencing its link to tissue “overgrowth.” The Hippo pathway has been shown to regulate cell death and cell growth, thus playing a role in the development or prevention of tumors. Junjie Chen, Ph.D., chair of Experimental Radiation Oncology, has revealed that the Hippo pathway can be manipulated to regulate the fuel, or glucose, that feeds all cells including those in tumors, thus presenting a potentially new avenue for cancer therapy. Read more here.