JAMA Oncology. Published online December 10, 2015. Bleicher et al,abstract; Chavez-MacGregor et al, abstract; Editorial
The publications revealed that patients whose treatment with adjuvant chemotherapy was initiated longer than 91 days following surgery experienced the worst overall survival (HR, 1.34; 95% CI, 1.15 - 1.57). In a subgroup analysis, the worst outcomes were seen for patients with TNBC (HR, 1.53; 95% CI, 1.17 - 2.00). Similar observations were reported for breast cancer–specific survival.
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