May 8, 2016 - In the most comprehensive molecular characterization to date of adrenocortical carcinoma, a rare cancer of the adrenal cortex, researchers extensively analyzed 91 cases for alterations in the tumor genomes. They identified several novel genetic mutations as likely mechanisms driving the disease. They also found that whole genome doubling, wherein a cell has one or more extra sets of chromosomes, as a probable driver of the disease. Read more here.
Mentioned study: Thomas J. Giordano, Roel G.W. Verhaak Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma Cancer Cell 29(5) p723–736, 9 May 2016
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