Squamous cell cancer offers distinct therapeutic challenges by virtue of presentation in older patients, its physical location in the chest, pattern of metastasis and association with comorbidities that can compromise treatment delivery and exacerbate toxicity.
Recently, molecular genotyping has led to the application of targeted agents for mutations prevalent in SqCC.9 This overview of the targeted treatments of squamous cell lung carcinoma highlights these recent molecular advances and discusses the potential role of newer molecular agents currently being evaluated for the treatment of advanced SqCC.
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