Thursday, 9 August 2018

Triple-negative breast cancer genes identified

Geneticists at the Mayo Clinic in Rochester, Minnesota have identified additional genes attributed to an increased risk of triple-negative breast cancer.  Following genetic tests on 11,000 patients with triple-negative breast cancer, the newly identified mutations, namely BARD1, BRCA1, PALB2 and RAD51D were linked to "high risk for triple-negative breast cancer and a greater than 20% lifetime risk of any type of breast cancer..." 


To read more about this study, click here


Source mentioned: Fasching PA, Loibl S, Hu C, Hart SN, Shimelis H, Moore R, et al. BRCA1/2 mutations and bevacizumab in the neoadjuvant treatment of breast cancer: response and prognosis results in patients with triple-negative breast cancer from the GeparQuinto study. J Clin Oncol. 2018 Aug 1; 36(22): 2281-2287.

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