Checkpoint target for colorectal cancer immunotherapy identified

New research from the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have discovered a checkpoint target for colorectal cancer immunotherapy. Upon investigating patient tumour genetic data, researchers found "abundant expression of ST2 in macrophages in tumor tissue samples from early to late-stage colorectal cancer."

To read more about this study, click here.

Study mentioned: Van Der Jeught K et al. ST2 as checkpoint target for colorectal cancer immunotherapy. JCI Insight 2020. doc: 10.1172/jci.insight.136073