New analysis of a phase 3 trial has unveiled that adding Ibrutinib (Imbruvica) to chemotherapy can improve survival rates for patients younger than 60 with diffuse large B-cell lymphoma (DLBCL). DLBCL is the most common type of lymphoma, occurring in 40% of lymphoma cases. According to Dr Louis M. Staudt, chief of the Lymphoid Malignancies Branch at the National Cancer Institute, "for years we have only had chemotherapy and rituximab to offer these patients...Now, we hope that adding Ibrutinib to current therapy may give younger patients a better chance of surviving this aggressive cancer."
To read more about this trial, click here.
Source mentioned: Wilson WH, Wright G, Huang DA, et al. Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL. Cancer Cell November 4, 2021. DOI: 10.1016/j.ccell.2021.10.006.
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