Findings from a recently completed phase 2 study by NCCTG N0147 alliance researchers "found significantly higher tumour infiltrating lymphocyte (TIL) densities in right- versus left-sided colon cancers." Following an extensive analysis and dichotomy of 1532 colon cancer patients, the study authors concluded that TILs "were second only to N stage for prediction of DFS [disease-free survival] and their relative contribution was substantially greater (16-fold) in right - vs. left-sided tumours."
To read more about this study, click here.
Source mentioned: Saberzadeh-Ardestani B, Foster NR, Lee HE, et al. Association of Tumor-infiltrating Lymphocytes (TILs) with Survival Depends on Primary Tumor Sidedness in Stage III Colon Cancers (NCCTG N0147) [Alliance]. Annals of Oncology; Published online 10 August 2022.
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