Tuesday 11 October 2022

Modest effectiveness of screening colonoscopy for the prevention of colorectal cancer: the NordICC study

 Results from the Nordic-European Initiative on Colorectal Cancer (NordICC) were recently unveiled at the United European Gastroenterology Week held in Vienna from October 8-11, 2022. Authors of the NordICC study state that "colonoscopy is considered to be more effective than sigmoidoscopy, but colonoscopy has not been adopted in many parts of the world, partly because evidence from randomized studies regarding the benefits is lacking."  The authors further emphasized that findings were significant in the 84,85 participants in NordICC (28,220 in the invited group, 11,843 of whom underwent screening, along with 56,365 participants in the usual-care group: "during a median follow-up of 10 years, 259 cases of colorectal cancer were diagnosed in the invited group as compared with 622 cases in the usual-care group." 

To read more about this study, click here.  

Sources mentioned: 

Bretthauer M, Løberg M, Wieszczy P, et al., for the NordICC Study Group. Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death. NEJM; Published online 9 October 2022. DOI: 10.1056/NEJMoa2208375

Dominitz JA, Robertson DJ. Understanding the Results of a Randomized Trial of Screening ColonoscopyNEJM; Published online 9 October 2022. DOI: 10.1056/NEJMe2211595

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