An ACCENT/IDEA pooled analysis conducted at the Bank of Cyprus Oncology Centre in Nicosia, Cyprus has shown that oxaliplatin-containing chemotherapy is both safe (in terms of toxicity management) and effective "in reducing recurrence rates in a large population [17,000] of older patients with stage III colon cancer." According to the trial's authors, led by Dr. Demetris Papamichael, while the median age of colon cancer diagnosis is 70 in western countries, only 14-20% of patients more than 70 years old have participated in adjuvant trials.
To read more about this trial, click here.
Source mentioned:
Gallois C, Shi Q, Pederson LD, et al. Oxaliplatin-Based Adjuvant Chemotherapy in Older Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 12 Trials. JCO; Published online 28 March 2024. DOI: https://doi.org/10.1200/JCO.23.0132
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