Results of DREAMM-7, a randomized phase III study, were recently published in the New England Journal of Medicine. According to DREAMM-7, "treatment with belantamab mafodotin, bortezomib and dexamethasone (BVd regimen) conferred a significant benefit...with respect to progression-free survival (PFS).." among melanoma patients. After a period of 18 months, overall survival for patients treated with the BVd regimen was 84% compared 73% in patients treated with daratumumab, bortezomib and dexamethasone (DVd). These findings indicate strong support for BVd as a preferred treatment option for patients with multiple myeloma.
To read more about this study, click here.
Sources mentioned:
- Hungria V, Robak P, Hus M, et al. for the DREAMM-7 Investigators. Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma. NEJM; Published online 1 June 2024. DOI: 10.1056/NEJMoa2405090
- Dimopoulos MA, Beksac M, Pour L, et al. for the DREAMM-8 Investigators. Belantamab Mafodotin, Pomalidomide, and Dexamethasone in Multiple Myeloma. NEJM; Published 2 June 2024. DOI: 10.1056/NEJMoa240340
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