As many cancer researchers can attest to, determining how and why cancer evades drug treatment is a continuous phenomenon. In a new study recently published online in Nature, a team from the Broad Institute, Dana-Farber Cancer Instiitute, and the Massachusetts General Hospital are focussing their research on the interaction between healthy cells and their cancer-causing counterparts. Findings from this study indicate that "normal cells that reside within the tumor, as part of the tumor microenvironment, may supply factors that help cancer cells grow and survive despite the presence of anti-cancer drugs."
More information on this study is available here.
Study mentioned: Straussman R et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion, Nature. 2012 Jul 4; [Epub ehad of print]. PMID: 22763439
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