Wednesday, 7 January 2015

A benign breast biopsy that is not so benign

A breast biopsy that results in a diagnosis of atypical hyperplasia is considered a benign finding, but that description obscures the riskiness of the condition, according to a special report published in the January 1, 2015, issue of the New England Journal of Medicine.

Dr Hartmann and coauthors, all of whom are from the Mayo Clinic in Rochester, Minnesota, report there is a cumulative incidence of breast cancer of 30% at 25 years of follow-up in their 698-patient cohort of women with atypical hyperplasia.

Study mentioned:
N Engl J Med. 2015 Jan;372(1):78-89. doi: 10.1056/NEJMsr1407164.
Atypical hyperplasia of the breast--risk assessment and management options.
Hartmann LC1, Degnim AC, Santen RJ, Dupont WD, Ghosh K.

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