Acquired resistance to immunotherapy

Advances in immunotherapy have resulted in significant clinical responses in some patients with cancer. However, one of the biggest challenges in cancer therapeutics is the development of resistant disease and disease progression on or after therapy. Nature Reviews Cancer asked three scientists to give their views on the current evidence for whether acquired resistance to immunotherapy exists in patients and the future challenges posed by immunotherapy. Below we present some of the answers provided by scientists from the US National Cancer Institute, QIMR Berghofer Medical Research Institute in Brisbane, and Memorial Sloan Kettering Cancer Center. Read more here.