On February 24, 2016 researchers have created a model of cancer in zebrafish that allows them to capture live images of tumors forming and growing, in some cases from a single cell. Using the model, the researchers characterized some of the early genetic and epigenetic changes associated with melanoma, the most deadly form of skin cancer.
In the fish, an important event in the development of melanoma was the activation, in differentiated pigment-producing cells, of a genetic program that normally occurs during embryonic development. The reprogramming of these mature cells, called melanocytes, gave them some of the characteristics of stem cells , such as the ability to grow and divide frequently, the researchers found. Read more here.
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