Findings of the DESTINY-Gastric01 randomized study, comparing trastuzumab deruxtecan vs. third line or later chemotherapy in HER2-positive gastric or gastro-esophageal cancer patients, was recently published in Nature Medicine. While the authors acknowledge that further investigations in larger studies is needed, "the biomarkers identified in this analysis are being investigated and validated in additional studies."
To learn more about DESTINY-Gastric01, click here.
Source mentioned: Shitara K, Bang Y-J, Iwasa S, et al. Trastuzumab deruxtecan in HER2-positive advanced gastric cancer: exploratory biomarker analysis of the randomized, phase 2 DESTINY-Gastric01 trial. Nature Medicine; Published online 14 May 2024. DOI: https://doi.org/10.1038/s41591-024-02992-x
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