A potentially powerful strategy for studying the significance of human genetic variants is to recruit people identified by previous genetic research as having particular variants. But that strategy poses ethical challenges to informed consent, as well as potential risks to the people recruited, and it is unlikely that there is a "one-size-fits-all" solution, concludes an article in the IRB: Ethics & Human Research. Read more here.
Study mentioned: Beskow LM, et al. IRB chairs' perspectives on genotype-driven research recruitment. IRB. 2012 May-Jun;34(3):1-10. PMID: 22830177
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