Monday 23 September 2013

Gene test shows promise for identifying aggressive prostate cancer

Researchers from Columbia University have identified 3 genes they used to predict whether prostate cancer in men with low-risk disease would stay low-risk, or become more of a threat. The researchers analyzed prostate biopsy specimens from 43 men who were followed for at least 10 years through active surveillance (with no immediate treatment). All the men had been diagnosed with low-risk prostate cancer, but in 14 of them the cancer eventually started to grow or become more aggressive. All 14 were correctly identified by the gene test. Read more here.

Study mentioned: Irshad S, et al. A molecular signature predictive of indolent prostate cancer. Sci Transl Med. 2013 Sep 11;5(202):202ra122. PMID: 24027026

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