Researchers at Roswell Park Cancer Institute have uncovered a new pathway by which cancer cells, such as in breast cancer, stimulate the expansion of myeloid-derived suppressor cells, a blood cell population known to interfere with the body’s anti-tumor response. The findings, published in The Journal of Clinical Investigation, shed new light on the pathological events that fuel tumor growth and could lead to the development of new therapies to hinder it. Read more here.
Study mentioned: Waight JD, et al. Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. J Clin Invest. Published online September 16, 2013.
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