Researchers at the Spanish National Cancer Research Centre (CNIO) performed the first exome sequencing for non-infiltrating bladder cancer. The results, published online in the Nature Genetics, reveal new genetic pathways involved in the disease, such as cellular division and DNA repair, as well as new genes that might be crucial for understanding the biology of this illness and its evolution. The genetic signature of these patients may be a first step towards improving patient management. Read more here.
Study mentioned: Balbás-Martínez C, et al. Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy. Nat Genet. 2013 Oct 13. [Epub ahead of print] PMID: 24121791
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