Dartmouth researchers develop new approach to chronic lymphocytic leukemia treatment

Dartmouth researchers have developed a novel and unique approach to treating Chronic Lymphocytic Leukemia (CLL). The researchers, led by Alexey V. Danilov, MD, PhD, assistant professor at the Geisel School of Medicine at Dartmouth and Hematologist-Oncologist at the Norris Cotton Cancer Center, modeled the lymph node microenvironment where CLL cells are found in the laboratory. They were able to disrupt the activity of a pathway (NF-kappaB) that ensures the survival and resistance of the CLL cells in such microenvironments. Read more here.