An international team of researchers has found that abnormal changes (mutations) to a gene called PALB2 increase the risk of breast cancer much more than previously thought. According to the study published in the August 7, 2014 issue of the New England Journal of Medicine, women with this gene mutation have a risk anywhere from 5 times to 9 times as high as women in the general population. The mutation was previously thought to raise risk by about 2 to 4 times.
Study mentioned:
Breast-Cancer Risk in Families with Mutations in PALB2. Published in the August 7, 2014 issue of the New England Journal of Medicine. First author A. C. Antoniou, PhD, University of Cambridge, UK.
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