Projected estimates of cancer in Canada 2024

 New research published in the Canadian Medical Association Journal summarizes the expected impact of cancer in Canada in 2024, including projections of new cancer cases and mortality, arranged according to gender and province/territory for 23 different types of cancer.  

Projected numbers for 2024 include 247,100 cancer diagnoses and 88,100 cancer deaths in Canada.  While rates of lung, colorectal, and prostate cancer are expected to decrease, other cancers, including liver, bile duct, kidney, melanoma, and non-Hodgkin lymphoma are expected to rise. 

To learn more about this research, click here. 

Source mentioned: 

Darren R. Brenner, Jennifer Gillis, Alain A. Demers, Larry F. Ellison, Jean-Michel Billette, Shary Xinyu Zhang, JiaQi Leon Liu, Ryan R. Woods, Christian Finley, Natalie Fitzgerald, Nathalie Saint-Jacques, Lorraine Shack, Donna Turner

CMAJ May 2024, 196 (18) E615-E623; DOI: 10.1503/cmaj.240095

Datopotamab deruxtecan shows promising activity in heavily pretreated advanced HR-positive/HER2-negative and triple-negative breast cancers

 TROPION-PanTumor01, a phase I study on the effects of datopotamab deruxtecan on heavily pretreated advanced HR-positive/HER2-negative breast cancer and triple-negative breast cancer (TNBC) indicated a "confirmed objective response rate of 26.8% in patients with HR-positive/HER2-negative breast cancer and 31.8% in patients with TNBC." While the study authors acknowledge that the number of patients in each cohort (41 HR-positive/HER2-negative and 44 in TNBC) use of datopotamab deruxtecan is being compared with single-agent chemotherapy as a possible second or third line treatment option.  

To read more about this study, click here. 

Source mentioned: Bardia A, Krop IE, Kogawa T, et al. Datopotamab Deruxtecan in Advanced or Metastatic HR+/HER2– and Triple-Negative Breast Cancer: Results From the Phase I TROPION-PanTumor01 Study. JCO; Published online 23 April 2024: DOI: https://doi.org/10.1200/JCO.23.01909