Toronto scientists have discovered new ways that cells deal with the damage caused by chemotherapy, a finding that could improve treatments for patients. In this Canadian Cancer Society–funded study, the research team used a microscopic screening technology to study all the proteins in the cell and their response to specific chemotherapy drugs. This is the first time all the proteins in cells have been studied in this way, allowing scientists to better understand what happens inside a cell during chemotherapy. Read more here.
Study mentioned: Tkach JM, et al. Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol. 2012 Jul 29. [Epub ahead of print] PMID: 22842922
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