Thursday 9 August 2012

Stress may promote breast cancer cell colonization of bones

A study conducted at the Vanderbilt Center for Bone Biology have uncovered a link between stress and breast cancer colonization of bones. Dr. Florent Elefteriou and colleagues have, according to clinical evidence, correctly hypothesized that "sympathetic activation might remodel the bone environment and make it more favourable for cancer cells to metastasize." As a result, breast cancer patients exhibiting stress or depression following treatment had shorter survival times. Cardiovascular medicine (propanolol) "inhibits sympathetic nervous system signals", and is seen as a likely long-term treatment option.

To read more about this study, click here.

Study mentioned: Campbell JP et al. Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice. PLoS Biol. 2012 Jul 10(7) [EPub 2012 Jul 17]. PMID 22815651

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