Dr. Vito Quaranta, professor of cancer biology at Vanderbilt-Ingram Cancer Center, and his team have developed a new tool to observe cell behaviour in cancer patients. This new approach analyzes how cancer cells respond to therapy and presents new possiblities with regards to refining personalized cancer treatments.
For instance, Dr. Quaranta's team has shown that erlotnib, "a targeted therapy that acts on an epidermal growth factor receptor mutated in some cancers...doesn't simply kill tumor cells as was previously assumed." The ability to predict tumor response allows for the possiblity of customizing various therapeutic treatments according to the individual patient's needs.
To read more about this tool, click here.
Study mentioned: Tyson DR, Garbett, SP, Frick PL, Quaranta V. Fractional proliferation: A method to deconvolve cell population dynamics from single-cell data. Nat Methods. 2012 Aug 12 [Epub ahead of print]. PMID 22886092
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