A recent study found that ROS1 fusion-positive patients tended to be younger never smokers with a histologic diagnosis of adenocarcinoma. However, there is no evidence strong enough to support this finding as far due to a very low frequency of ROS1 fusions in non-small cell lung cancer. Additionally, ROS1 fusions were identified in squamous cell carcinoma histology, and moreover in several studies only some of ROS1 fusion-positive patients were never smokers. Read more here.
Study mentioned: Cai W, et al. ROS1 fusions in Chinese patients with non-small-cell lung cancer. Ann Oncol. 2013 Mar 20. [Epub ahead of print] PMID: 23514723
No comments:
Post a Comment