Tuesday 23 April 2013

Hundreds of alterations and potential drug targets to starve tumors identified

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, also identified hundreds of potential drug targets that could cut off a tumor’s fuel supply or interfere with its ability to synthesize essential building blocks. Read more here.

Study mentioned: Hu J, et al. Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Nat Biotechnol. 2013 Apr 21. doi: 10.1038/nbt.2530. [Epub ahead of print] PMID: 23604282

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