Monday, 1 April 2013

New findings may lead to better predictions of breast cancer risk in women with inherited mutations

An international team led by Memorial Sloan-Kettering cancer geneticist Kenneth Offit has identified additional genetic variations that change a woman’s risk of developing breast cancer. This information will allow investigators to create a model to more accurately predict the breast cancer risk of an individual woman. The model will be specific to women with mutations in the gene BRCA2, although it may be extended to include BRCA1 as well. Read more here.

Study mentioned: Gaudet MM, et al. Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk. PLoS Genet 9(3): e1003173. Published online March 27, 2013.

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