Salk scientists deliver a promising one-two punch for lung cancer

Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy–with analogs already in use for other diseases–doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells. “There really have been no effective treatments to target the KRAS mutation so far,” says Inder Verma, a professor in the Laboratory of Genetics and American Cancer Society Professor of Molecular Biology. “We found a drug combination that successfully targets KRAS and stops tumor growth in the mouse model.” Read more here.