A recent study recruited 376 patients with cancer and fatigue. Subjects were randomly assigned to consume a drink containing two grams of L-carnitine daily or a placebo drink. The study lasted for four weeks, and daily fatigue was evaluated by the Brief Fatigue Inventory questionnaire. Compared to the placebo group, the L-carnitine group did not have significant changes in fatigue at the end of four weeks. Moreover, L-carnitine supplementation did not impact depression or pain in the cancer patients. Further research is necessary. Read more here.
Study mentioned: Cruciani RA et al. L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial. J Clin Oncol. 2012 Sep 17. [Epub ahead of print] PMID: 22987089
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