In a major breakthrough for uterine serous carcinoma, Yale researchers have defined the genetic landscape of USC tumors, findings that point to new treatment opportunities. The collaborative team—which included researchers with expertise in gynecological cancer, genomics, and computational biology— identified a number of new genes that are frequently mutated in USC. The results of this comprehensive genetic analysis of USC are published in Proceedings of the National Academy of Science. Read more here.
Study mentioned: Zhao S, et al. Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. PNAS 2013. Published ahead of print January 28, 2013.
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