Tuesday 16 July 2013

DNA flaw boosts cancer risk from diabetes: study

A DNA flaw may explain why people with Type 2 diabetes are more prone to blood cancers than the rest of the population, according to a recent study. Doctors have long known that Type 2 diabetes is associated with leukaemia and lymphoma, but the reasons for this have been unclear. Researchers in France and Britain, looking at blood samples from nearly 7,500 people, including 2,200 patients with Type 2 diabetes, suggest the answer lies in cellular mutations called clonal mosaic events (CMEs). Read more here.

Study mentioned: Bonnefond A, et al. Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications. Nat Genet. 2013 Jul 14. [Epub ahead of print] PMID: 23852171

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