Low-dose aspirin could be an alternative to colectomy for preventing colorectal cancer in familial adenomatous polyposis

 Researchers in Japan recently reported that "low-dose aspirin safely suppressed the recurrence of colorectal polyps larger than 5mm in patients with familial adenomatous polyposis (FAP)."  Prior to the study's release, colectomy was the only recognized treatment for preventing colorectal cancer in FAP patients, despite reducing quality of life.  

To read more about this study, click here. 

Sources mentioned: 

Ishikawa H, Mutoh M, Sato Y, et al. Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial. The Lancet Gastroenterology & Hepatology; Published online 1 April 2021. DOI: https://doi.org/10.1016/S2468-1253(21)00018-2

Lynch PM. Low-dose aspirin and mesalazine for patients with familial adenomatous polyposis. The Lancet Gastroenterology & Hepatology; Published online 1 April 2021. DOI: https://doi.org/10.1016/S2468-1253(21)00102-3