A recently published prospective study conducted in the Department of Epidemiology and Cancer Control at St. Jude's Children's Research Hospital in Memphis, Tennessee, indicates that frail young adult survivors of childhood cancers "experienced significantly larger declines than non frail survivors in memory, attention, processing speed, and executive function domains." The study, conducted on childhood cancer survivors between 18-45 years old with at least 10 years from diagnosis supported background research findings where cancer-related neurocognitive impairment occurs in up to 35% of childhood cancer survivors. However, study authors acknowledged that "further research is needed to understand the shared biologic pathways underlying frailty and neurocognitive function."
To read more about this study, click here.
Source mentioned:
Williams ALM, Krull KR, Howell CR, et al. Physiologic Frailty and Neurocognitive Decline Among Young-Adult Childhood Cancer Survivors: A Prospective Study From the St Jude Lifetime Cohort. JCO; Published online 20 July 2021. DOI: 10.1200/JCO.21.00194
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