How cells communicate to activate Notch - Essential research for design of potential therapeutics for numerous Notch-related diseases, in particular cancer

The Notch signaling system allows cells to directly talk to each other to program almost every cell type in the body. Now, researchers have shown for the first time that the mechanical force produced by cell-cell interactions is critical for programming by the Notch signaling system. Researchers show for the first time that the mechanical force produced by cell-cell interactions is critical for programming by the Notch signaling system. More information about the studies may be found here.