Wednesday 20 June 2012

Researchers identified a specific breast cancer bone metastasis-supporting gene

In this week's Journal of Biological Chemistry "Paper of the Week," Roger Gomis and colleagues at the Institute for Research in Biomedicine in Barcelona, Spain investigated how breast cancer cells migrate to bone. In particular, they examined the role of NOG, a gene important to proper bone development. Previously, NOG was associated with bone metastasis in prostate cancer, but its specific role in breast cancer to bone metastasis remained unknown. Read more here.

Study mentioned: Tarragona M, et al. Identification of NOG as a specific breast cancer bone metastasis-supporting gene. J Biol Chem. 2012 Jun 15;287(25):21346-55. Epub 2012 Apr 30. PMID 22547073

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