Thursday, 15 November 2012

Detection, analysis of 'cell dust' may allow diagnosis, monitoring of brain cancer

A novel miniature diagnostic platform using nuclear magnetic resonance (NMR) technology is capable of detecting minuscule cell particles known as microvesicles in a drop of blood. Microvesicles shed by cancer cells are even more numerous than those released by normal cells, so detecting them could prove a simple means for diagnosing cancer. In a study published in Nature Medicine, investigators at the Massachusetts General Hospital (MGH) Center for Systems Biology (CSB) demonstrate that microvesicles shed by brain cancer cells can be reliably detected in human blood through a combination of nanotechnology and their new NMR-based device. Read more here.

Study mentioned: Shao H, et al. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat Med. 2012 Nov 11. [Epub ahead of print] PMID: 23142818

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