Wednesday 6 February 2013

Antibody hinders growth of Gleevec-resistant gastrointestinal tumors in lab tests, researchers say

An antibody that binds to a molecule on the surface of a rare but deadly tumor of the gastrointestinal tract inhibits the growth of the cancer cells in mice, according to researchers at the Stanford University School of Medicine. The effect remains even when the cancer cells have become resistant to other treatments, and the findings may one day provide a glimmer of hope for people with the cancer, known as gastrointestinal stromal tumor, or GIST. Read more here.

Study mentioned: Edris B, et al. Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci U S A. 2013 Feb 4. [Epub ahead of print] PMID: 23382202

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