Wednesday 6 February 2013

Blood vessel cells coax colorectal cancer cells into more dangerous state

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at The University of Texas MD Anderson Cancer Center report online in Cancer Cell. Read more here.

Study mentioned: Lu J, et al. Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1. Cancer Cell. 2013 Jan 29. [Epub ahead of print] PMID: 23375636

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