Wednesday 13 February 2013

Mouse model of clear cell sarcoma improves understanding of rare, deadly cancer

Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises. The mouse model also can potentially speed the development of drugs to target genes that must be activated for the cancer to form. Read more here.

Study mentioned: Straessler KM, et al. Modeling Clear Cell Sarcomagenesis in the Mouse: Cell of Origin Differentiation State Impacts Tumor Characteristics. Cancer Cell. Online 11 February 2013.

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