Cathflo (alteplase) - Particulate matter observed in some vials: additional instructions for use - Notice to Hospitals

Hoffmann-La Roche Limited (Roche), in consultation with Health Canada, would like to inform you that visible rubber stopper particulates have been observed in some vials of CATHFLO (alteplase) after reconstitution. CATHFLO is a serine protease indicated for the restoration of function to central venous access devices. Read more here.