Thursday, 30 May 2013

Shape-shifting nanoparticles flip from sphere to net in response to tumor signal

Scientists at the University of California, San Diego, have designed tiny spherical particles to float easily through the bloodstream after injection, then assemble into a durable scaffold within diseased tissue. An enzyme produced by a specific type of tumor can trigger the transformation of the spheres into netlike structures that accumulate at the site of a cancer, the team reports in the journal Advanced Materials. Read more here.

Study mentioned: Chien MP, et al. Enzyme-Directed Assembly of a Nanoparticle Probe in Tumor Tissue. Adv Mater. 2013 May 28. [Epub ahead of print] PMID: 23712821

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