Friday 6 December 2013

Blocking antioxidants in cancer cells reduces tumor growth in mice

In the Journal of Clinical Investigation, Navdeep Chandel and colleagues from Northwestern University report the effects of a SOD1 pharmacological inhibitor on non-small-cell lung cancer (NSCLC) cells. The inhibitor, called ATN-224, stunted the growth of human NSCLC cells in culture and induced their death. Read more here.

Study mentioned: Glasauer A, et al. Targeting SOD1 reduces experimental non-small-cell lung cancer. J Clin Invest. 2013 Dec 2. [Epub ahead of print] PMID: 24292713

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