Monday 23 December 2013

Muscle-invasive and non-muscle invasive bladder cancers arise from different stem cells

A University of Colorado Cancer Center study shows that progenitor cells that create MI bladder cancer are different than the progenitor cells that create NMI bladder cancer. Though these two cancers grow at the same site, they are different diseases. “This work provides an important new perspective on how we look at bladder cancer biology,” says Dan Theodorescu, MD, PhD, director of the University of Colorado Cancer Center and the study’s senior author. Read more here.

Study mentioned: Dancik GM, et al. A cell of origin gene signature indicates human bladder cancer has distinct cellular progenitors. Stem Cells. 2013 Dec 19. [Epub ahead of print] PMID: 24357085

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