A panel of 55 genes, almost all of which are impacted by the loss of a particular protein, appears to predict if breast cancer will become invasive, leading to poorer survival, researchers at Georgetown Lombardi Comprehensive Cancer Center report in PLOS ONE. The panel represents loss of a powerful tumor suppressor gene, SYK, as well as genetic alterations in 51 other genes that are directly affected by the loss of a copy of the SYK gene and the absence of its protein. Read more here.
Study mentioned: Blancato J, et al. SYK Allelic Loss and the Role of Syk-Regulated Genes in Breast Cancer Survival. PLoS One. 2014 Feb 11;9(2):e87610. PMID: 24523870
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