Wednesday, 5 February 2014

Analysis of somatic point mutations in exome sequences

A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than previously thought. By analysing the genomes of thousands of patients' tumours, a Broad Institute-led research team has discovered many new cancer genes — expanding the list of known genes tied to these cancers by 25%. Read more here.

Study mentioned: Lawrence MS, et al. Discovery and saturation analysis of cancer genes across 21 tumour types. Nature. 2014 Jan 23;505(7484):495-501. PMID: 24390350

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