Friday 9 November 2012

Discovery of gene switch important in cancer

Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the switches that regulate the expression of genes play a major role in the development of cancer. In a study, published in Science, they have investigated a gene region that contains a particular single nucleotide variant associated with increased risk for developing colorectal and prostate cancers, and found that removing this region caused dramatic resistance to tumor formation. Read more here.

Study mentioned: Sur IK, et al. Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors. Science. 2012 Nov 1. [Epub ahead of print] PMID: 23118011

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