Gliomas are the most common form of brain tumor. In the Journal of Clinical Investigation, researchers led by Antonio Iavarone at Columbia University report on the role of ID proteins in glioma. Using a mouse model of glioma, Iavarone and colleagues found that ID proteins were also responsible for retaining GICs in the extracellular niche that allowed them to maintain their cancer promoting properties. Read more here.
Study mentioned: Niola F, et al. Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. J Clin Invest. 2012 Dec 17. [Epub ahead of print] PMID: 23241957
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